Two-dimensional chromatography is a type of chromatographic technique in which the injected sample is separated by passing through two different separation stages.

6 days ago · Two-dimensional liquid chromatography (2D-LC) has evolved into a versatile analytical tool capable of resolving chemically complex samples that challenge conventional …

Nov 28, 2016 · In this tutorial, we aim to capture the state of the art of two-dimensional liquid chromatography (2D-LC) by highlighting key background that will help readers understand …

One-dimensional (1D) chromatography and two-dimensional (2D) chromatography offer well-established instrumental platforms that produce separations of chemical compounds in …

Using a shifted second dimension gradient means that over the course of the 2D-LC run, the second dimension gradient is changed in order to adapt to the hydrophobicity of the …

Nov 16, 2023 · This Primer introduces comprehensive 2D chromatography, including instrument setups for different applications.

What is Multidimensional Chromatography? Multidimensional chromatography uses a combination of several chromatography techniques, separation modes, and columns to …

Aug 17, 2025 · Development of 2D-LC methods offers plentiful opportunities for innovation in instrumentation, automation, and data analysis. This article reviews literature related to 2D-LC …

Data structure for 2D chromatographic data. The data dimensions include first and second dimension retention times and may include spectral information (m/z or wavelength) and/or …

Sep 14, 2023 · The study describes 2D chromatographic techniques for GC-MS, 2D-LC, 2D-GC, 2D-CE, FTIR, and 2D-IR. Moreover, their advantages, challenges, and previous analytical …