The renin-angiotensin system (RAS) remains a cornerstone of cardiovascular and renal physiology, orchestrating vital aspects of blood pressure regulation and fluid-electrolyte balance. At the heart of ...

Research in the Molecular Physiology Laboratory (MPL) focuses on the neurogenic mechanisms of hypertension and associated cardiovascular diseases with particular emphasis on developing novel targets ...

Testing for aldosterone levels may hold the key to treatment-resistant hypertension and many other cardiac conditions, but ...

Initial evidence of the existence of renin, which is an angiotensinogenase enzyme secreted by the kidney, was presented to the medical community more than 100 years ago. Nevertheless, the significance ...

In this rapidly evolving setting, clinicians are weighing the alleged harm of continuing these medications in patients for whom ACE inhibitors and ARBs have known benefit against the harm to their ...

The scientists discovered that the hormone angiotensin II, also known as ang II, helps control renin by affecting calcium ...

ACE inhibitors work by interfering with the body's renin-angiotensin-aldosterone system (RAAS). RAAS is a complex system responsible for regulating the body's blood pressure. The kidneys release an ...

Angiotensin-converting–enzyme (ACE) inhibitors and angiotensin-receptor blockers are used commonly in clinical practice to treat hypertension and decrease cardiovascular events in high-risk patients.

A new study has identified a critical "pressure sensor" inside the kidney that helps the body control blood pressure and ...