Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...

The success or failure of assisted reproduction can be influenced by many factors, both nonmodifiable (age, ovarian reserve) and modifiable (body weight, lifestyle habits). Smoking belongs to the ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

The stresses that come with aging, chemotherapy treatments, and environmental exposures all threaten fertility. But what if there were a way to preserve women's limited egg supply? Researchers ...

Researchers at the Center for Genomic Regulation (CRG) in Barcelona have discovered a mechanism that may explain how immature human egg cells (oocytes) are able to survive for long periods of time ...

The stresses that come with aging, chemotherapy treatments, and environmental exposures all threaten fertility. But what if there were a way to preserve women's limited egg supply? Researchers ...