The replication control system of plasmid R6-5 has been investigated by characterization of high-copy-number mutant miniplasmids, development of an in vivo assay for the site of action or ``target'' ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 15 (Jul. 22, 2003), pp. 8692-8697 (6 pages) The DnaA replication initiation protein has been shown to be ...
Plasmid DNA (pDNA) is a key material for producing gene therapies, mRNA and DNA vaccines. The alkaline lysis process to isolate pDNA is simple on the benchtop, but it’s challenging at industrial scale ...